How Long Does Methadone Detox Take to Complete?

Medical Providers:
Dr. Michael Vines, MD
Ray Hamilton, DNP, PMHNP-BC, FNP-C
Last Updated: August 16, 2025

Methadone is a long-acting opioid commonly used to treat opioid addiction, but stopping its use can lead to difficult withdrawal symptoms. Many people ask, “How long does methadone detox take?”—especially when preparing to enter recovery. The answer depends on several factors, including how long you’ve been taking methadone, your dosage, and whether you’re going through a medically supervised detox.

This article explores the methadone detox timeline, what to expect during withdrawal, and how treatment programs can help ease the process.

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What Is Methadone Dependence?

Methadone is prescribed to reduce cravings and withdrawal symptoms in people with opioid use disorder. While it can be effective for treating opioid addictions, long-term use can lead to methadone dependence. Over time, your body adjusts to the drug and relies on it to function. When you stop taking methadone—especially suddenly—it can result in uncomfortable and even dangerous withdrawal symptoms.

That’s why methadone detox is best done with professional support. A treatment center can help manage both the physical and emotional effects of withdrawal.

How Long Does Methadone Detox Take?

Methadone detox typically takes between 2 to 3 weeks, but some people may experience symptoms for much longer. Because methadone is a long-acting opioid, it stays in the body longer than many other substances, which means detox and withdrawal may take more time.

Here’s a general overview of the methadone detox timeline:

  • Day 1–3: Withdrawal symptoms may begin 24 to 36 hours after the last dose. These early symptoms include anxiety, restlessness, sweating, and muscle aches.
  • Day 4–10: Symptoms usually peak during this period. You may experience nausea, diarrhea, insomnia, and intense cravings.
  • Day 11–21: Symptoms gradually start to fade, but some discomfort—like fatigue, mood swings, or difficulty sleeping—can continue.
  • After 3 weeks: Many people begin to feel more stable, but emotional symptoms like depression or anxiety may linger, especially without proper support.

Keep in mind that how long methadone withdrawal lasts varies for everyone. Factors such as age, general health, mental health, dose of methadone, and duration of use all play a role.

Wondering how long detox will take? Explore your options with professional help.

Common Methadone Withdrawal Symptoms

During detox, individuals may experience a range of physical and psychological symptoms. These may include:

  • Nausea and vomiting
  • Chills and sweating
  • Abdominal cramps
  • Insomnia
  • Anxiety and irritability
  • Depression
  • Muscle aches
  • Strong drug cravings

Methadone withdrawal symptoms can become intense, particularly during the peak detox phase. That’s why seeking a medical detox for methadone is highly recommended to ensure safety and comfort.

Experiencing methadone withdrawal signs? Learn what symptoms to expect during detox.

Why Is Medical Detox Crucial?

Some people try to stop methadone “cold turkey,” but this can be risky and lead to relapse or medical complications. A medical detox program provides 24/7 supervision, medication to ease symptoms, and support for both the body and mind. These programs are designed to safely manage the methadone detox process while reducing discomfort.

At a licensed addiction center, medical detox may include:

  • Gradual tapering of methadone to reduce shock to the system
  • Medications to manage pain, sleep issues, or cravings
  • Mental health support to address anxiety, depression, or trauma
  • Nutritional support to help the body heal

Detox is just the first step, but it lays the foundation for long-term recovery. A structured setting improves safety and success rates compared to trying detox alone.

Cold turkey isn't the safest option. Discover how medical detox improves outcomes.

What Affects the Methadone Detox Timeline?

Several factors influence the duration and severity of methadone detox:

  • Length of methadone use: The longer you’ve been on methadone, the longer detox may take.
  • Dosage: Higher doses usually result in more intense symptoms.
  • Overall health: Physical and mental health play a big role in how your body handles withdrawal.
  • Substance use history: If you’ve used other opioids or substances, detox may be more complex.
  • Support system: Emotional and medical support can significantly impact your recovery experience.

No two detox journeys are exactly alike. That’s why professional treatment programs personalize detox plans based on your unique needs.

Detox looks different for everyone. Let our team personalize your recovery path.

The Importance of Ongoing Treatment

Once the physical detox is complete, it’s essential to continue care with a long-term recovery plan. Detox addresses the body’s dependence, but it doesn’t solve the emotional or behavioral sides of addiction.

Effective treatment programs include:

  • Therapy and counseling: To help you understand the root causes of your substance use
  • Group support: Connecting with others who understand your journey
  • Holistic services: Yoga, meditation, nutrition, and exercise for full-body healing
  • Aftercare planning: Relapse prevention strategies and continuing support

Without follow-up care, the risk of returning to methadone treatment or using other opioids increases.

What Should You Know About Tapering Off Methadone?

One of the safest ways to stop methadone is through tapering—a gradual dose reduction supervised by medical professionals. This method minimizes withdrawal symptoms and gives your body time to adjust.

A personalized tapering schedule may last for several weeks or even months, depending on the dose of methadone and your individual response. This is a core part of the methadone detox process at many reputable treatment centers.

Is Detox Right for You?

If you or a loved one is struggling with methadone dependence, know that help is available. Detox isn’t easy, but with the right care and support, it’s possible to overcome the physical side of addiction and move toward long-term recovery.

Signs that you may need detox include:

  • Taking methadone longer than prescribed
  • Feeling unable to function without it
  • Experiencing withdrawal when skipping a dose
  • Wanting to stop but being afraid of the symptoms

An accredited treatment center can help you decide the best next steps based on your history, goals, and overall health.

Methadone Detox Near Me: Start Your Recovery Today

The question, how long does methadone detox take, has no one-size-fits-all answer. However, most people start to feel better within a few weeks with the right treatment and support. Detox is only the beginning—true recovery includes addressing mental health, building coping skills, and staying committed to your journey.

If you’re ready to begin or help a loved one take the first step, Scottsdale Detox offers compassionate, evidence-based care tailored to your unique situation. With a team of experts and a safe, welcoming environment, you don’t have to face withdrawal from methadone alone.

Ready to start methadone detox with confidence? Watch expert insights on recovery and next steps.