An estimated 1.7 million Americans used kratom in 2021, and approximately 31% of kratom users develop at least one substance use disorder, according to research from the National Institutes of Health. When kratom is combined with alcohol, the risks intensify dramatically. Both substances affect the central nervous system, and mixing them creates unpredictable interactions that can lead to severe sedation, respiratory depression, and overdose.
Kratom’s dose-dependent effects—stimulating at lower doses and sedating at higher doses—compound alcohol’s depressant properties, putting physical health at serious risk. Regularly using kratom and alcohol together increases risks to mental health and can accelerate the development of substance use disorders, making Kratom detox essential for safe recovery.



