7-hydroxy (7-OH), one of the most potent metabolites found in kratom products, has gained attention because of its strong opioid-like effects and the way it interacts with mu opioid receptors. Even though many kratom items are sold as everyday dietary supplements, their impact can feel much stronger than what most people expect.
In the United States, about 0.7% of individuals aged 12 or older — roughly 1.9 million people — reported using kratom in the past year according to the 2022 National Survey on Drug Use and Health.



