Fentanyl, a synthetic opioid, has gained notoriety for being 50 times more potent than heroin, and 100 times more potent than morphine. The use of Fentanyl led to a surge in opioid-related deaths and substance use disorders across the United States. In fact, according to the Centers for Disease Control and Prevention, more than 150 people die from synthetic opioid overdose every day. In this article, we will dive into the origins of this deadly substance and how it affects the body.