Detox from fentanyl and heroin is a critical first step on your path to recovery. When you commit to a tailored protocol, you reduce risks, ease withdrawal discomfort and set the stage for lasting sobriety. In this guide you’ll find clear, evidence-based strategies—from understanding opioid withdrawal timelines to choosing the right medical detox center and planning aftercare. Whether you live in New York State or elsewhere, these insights will help you navigate detox safely and confidently.
Understand opioid withdrawal
Timeline of symptoms
Opioid withdrawal symptoms typically begin within 8 to 24 hours after last use of short-acting opioids such as heroin, and within 12 to 48 hours for long-acting formulations like methadone. Acute withdrawal can last 4 to 10 days for heroin and up to 20 days for methadone. After acute symptoms subside, you may experience a protracted withdrawal phase lasting up to six months, marked by low mood, sleep disturbances and cravings [1].
Severity assessment
Assessing your withdrawal severity helps guide medication choices and monitoring frequency. The Clinical Opioid Withdrawal Scale (COWS) scores symptoms such as pupil size, tremor and gastrointestinal distress on a 0–47 scale:
- 5–12 mild withdrawal
- 13–24 moderate withdrawal
- 25–36 moderately severe withdrawal
- 37+ severe withdrawal
A COWS score above 13 often indicates the need for medication-assisted treatment to alleviate symptoms and prevent complications [1].
Choose medical detox center
Benefits of professional oversight
Undergoing detox in a medically supervised setting reduces the risk of severe complications such as dehydration, autonomic hyperactivity or cardiac stress. Trained clinicians can adjust medication doses in real time, monitor vital signs and address co-occurring psychiatric disorders. You’ll also receive education on overdose prevention, including community naloxone training, which is vital when detoxing from opioids [2].
State-certified programs
If you live in New York State, you have access to 12 state-certified Addiction Treatment Centers (ATCs) operated by the Office of Addiction Services and Supports. These facilities provide medication-assisted treatment, individualized detox plans and aftercare referrals regardless of your county of residence [2]. When evaluating a center, look for:
- 24/7 medical supervision
- Medication-assisted detox (buprenorphine, methadone, clonidine)
- Integrated psychiatric assessment
- Tobacco-free environment
Use medication-assisted treatment
Buprenorphine protocols
Buprenorphine is often the first-line medication for moderate to severe opioid withdrawal. It’s started 12 to 18 hours after last use of heroin or short-acting opioids to avoid precipitated withdrawal. Typical induction doses range from 4 to 12 mg sublingually, with subsequent adjustments based on symptom relief. The Mainstreaming Addiction Treatment Act of 2022 allows all DEA-registered providers with Schedule III authority to prescribe buprenorphine, expanding access to this evidence-based option [3].
Methadone dosing
Methadone, a long-acting opioid agonist, can ease withdrawal over a 10–20 day detox period. Initial administration often starts at 10 mg orally or intravenously every 4–6 hours, divided into smaller doses on day 1 to reduce overdose risk. Clinicians then titrate daily doses up to a maximum of 40 mg in 24 hours before considering maintenance treatment.
Non-opioid options
Lofexidine hydrochloride, approved by the FDA in 2018, is a non-opioid alpha-2 adrenergic agonist that reduces sympathetic outflow and eases acute withdrawal symptoms for up to 14 days [3]. Clonidine can also relieve many physical symptoms but requires blood pressure monitoring and should not be given simultaneously with opioid substitution therapy [1].
Manage withdrawal symptoms
Symptomatic medications
Alongside primary detox medications, you may use secondary drugs to target specific symptoms:
| Symptom | Medication | Typical dose |
|---|---|---|
| Diarrhea | Loperamide | 4 mg initially, then 2 mg every 4 h |
| Nausea, vomiting | Promethazine | 25 mg orally every 6 h |
| Myalgia, pain | Ibuprofen | 400–600 mg every 6–8 h |
| Hypertension | Clonidine | 0.1–0.2 mg every 6–8 h |
Monitoring vital signs
Continuous monitoring of blood pressure, heart rate, temperature and fluid balance prevents complications such as hypotension or dehydration. You’ll have scheduled vital checks and access to IV fluids if needed. Clinicians adjust your regimen based on real-time data, ensuring safe symptom management.
Psychosocial interventions
Behavioral support accelerates your recovery and reduces relapse risk. Common interventions include:
- Cognitive behavioral therapy to reframe negative thoughts
- Motivational interviewing to strengthen your commitment
- Group therapy for peer encouragement
These interventions should begin during detox and continue into aftercare to address emotional triggers and build coping skills.
Plan your aftercare
Protracted withdrawal phase
After acute symptoms resolve, you enter a protracted phase lasting weeks to months. During this time you may face lingering cravings, insomnia and anhedonia. Recognizing this phase helps you prepare for downward mood trends and seek timely support [1].
Psychosocial support
Building a robust support network is key. Options include:
- Outpatient counseling
- Peer recovery coaches
- Twelve-step fellowships or SMART Recovery groups
If you need outpatient care after detox, explore programs like Southern California Recovery Centers or specialized tiers such as suboxone taper detox scottsdale.
Relapse prevention strategies
Relapse prevention focuses on identifying high-risk situations and building coping plans:
- List triggers (stress, social pressure, environmental cues)
- Develop distraction and relaxation techniques
- Establish emergency contacts and safe spaces
Frequent follow-up appointments during early recovery help adjust your plan and maintain momentum.
Integrate supportive therapies
Holistic approaches
Complement medical detox with holistic modalities that promote wellness:
- Yoga and stretching to reduce muscle tension
- Mindfulness meditation for stress reduction
- Nutritional counseling to restore electrolyte balance
- Light exercise to boost mood and sleep quality
These practices reinforce your physical and emotional resilience as you progress through recovery.
Peer support groups
Engaging with peers who share your experiences fosters accountability and hope. Consider:
- Narcotics Anonymous meetings in your community
- Online forums for continuous support
- Family therapy sessions to rebuild trust and communication
Peer groups also provide a structured environment for practicing new coping skills.
Explore related detox programs
Multi-drug detox options
If you face polysubstance challenges, multi-drug protocols address dependencies on opioids, stimulants or benzodiazepines in one continuum of care. Facilities offering this approach include specialized centers in Scottsdale such as multi-drug detox scottsdale.
Substance-specific protocols
Every substance requires its own detox considerations:
- Stimulants: See detox for stimulants scottsdale
- Cocaine: Explore cocaine detox scottsdale az
- Prescription opioids: Learn about detox from prescription opioids scottsdale
- Prescription drug abuse: Review detox from prescription drug abuse
- Benzodiazepines: Check xanax benzodiazepine detox scottsdale
- Methamphetamine: Visit detox from meth scottsdale
- Alcohol and benzos: See detox protocol for alcohol + benzo
Choosing a program that specializes in your substance ensures the right medications, monitoring and therapy are in place.
Your recovery from detox of fentanyl and heroin begins with a personalized plan, medical expertise and ongoing support. By understanding withdrawal, selecting a certified detox center, using medication-assisted treatment and integrating holistic care, you give yourself the best chance for a safe, sustainable recovery journey.






