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In order to be safe, detox must be medically monitored by professionals trained to assist in the event of an emergency, as well as to ensure comfort and ease symptoms during withdrawal.

What is Tramadol Withdrawal?

Once a person develops a dependence to tramadol, stopping the drug will cause unpleasant withdrawal symptoms. Even using tramadol as prescribed by your doctor can lead to a physical dependence and therefore withdrawal symptoms.

Withdrawal happens after the body becomes chemically addicted, or altered, from taking tramadol on a continuous basis—even after only a few weeks. This happens because users develop a tolerance to the drug, meaning they must take more frequent and larger doses to feel the same effects, (ie. pain relief or euphoria) and to prevent feeling painful withdrawal symptoms. In response, the brain adapts to the constant presence of the drug and adjusts chemically.

Individuals also often abuse the drug to feel the relaxing, sedating effect it produces.

When an individual decides to discontinue the drug, they may experience withdrawal symptoms ranging from a minor headache to an increased heart rate.

It is important to enroll in a medical detox facility as soon as possible after ending tramadol use so you can be in a safe, medically supervised environment if withdrawal symptoms do surface.

How Is Tramadol Withdrawal Different from Other Opioids?

Tramadol withdrawal relieves pain differently than most opioids because it relieves pain through two mechanisms: stimulating opioids receptors in the brain, and inhibiting the reuptake of two neurotransmitters, serotonin and norepinephrine. The result is two forms of withdrawal that may be experienced: traditional opioid withdrawal and atypical opioid withdrawal syndrome. This is unique as it does not occur with other opioids.

Traditional opioid withdrawal symptoms include:

  • Nausea
  • Vomiting
  • Gastrointestinal pain
  • Diarrhea
  • Body pains
  • Muscle aches

Atypical opioid withdrawal syndrome symptoms include:

  • Confusion and disorientation
  • Hallucinations
  • Intense paranoia
  • High anxiety and panic attacks
  • Depersonalization
  • Unusual sensory experiences (such as numbness and prickling in the extremities)
Long-term abuse can lead to more pronounced side effects, but the sooner the detoxification process begins, the sooner you or your loved one can recover.

These atypical symptoms are generally not life-threatening; however, they do put the individual at high risk of making bad decisions or putting themselves in dangerous situations. Therefore, it is highly recommended to detox in an inpatient, medically-supervised detox center such as Scottsdale Detox.

Tramadol Withdrawal Timeline

  • Days 1-3

    Onset of general withdrawal symptoms, such as feelings of pins and needles, sweating, nervousness, nausea, anxiety, palpitations, insomnia and drug cravings.

  • Days 4-7

    Drug cravings persist, along with disorientation, confusion, and insomnia.

  • Days 8-14

    Symptoms should be fairly mild. Depression, anxiety, and irrational thoughts may still be present.

Tramadol Detox

If you are physically dependent or addicted to tramadol and would like to detox in a safe, comfortable environment, Scottsdale Detox Center is here to help.

Our traditional and holistic medical approaches treat the whole mind, body, and soul. Learn More

After Tramadol Detox

It is highly recommended for an individual who has just completed detox to continue the continuum of care for addiction. This involves enrolling in a rehabilitation center or finding an alternative aftercare program.
The reasoning behind this is that drug and alcohol detoxification focuses on removing a physical dependence on a substance. To truly have a sustainable recovery, you also need to cure the mental aspect of addiction, which can require rehab.
At Scottsdale Detox Center, we offer a licensed residential detox, where you can begin your process. We will also work with you to build a after care plan.



Struggling with addiction is hard enough, and trying to do it alone is practically impossible. Misuse of drugs or alcohol hides the underlying causes of your addiction and these will continue to disrupt your life until they are uncovered and addressed.

If you are reading this right now and need to change things in your life, please call us now. We understand how you feel and the struggle to pick up the phone. Our staff recognizes that people who try to quit by themselves oftentimes get frustrated and feel helpless when they can’t. You can, and we can help.


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